Targeting the gut barrier: Identification of a homing peptide sequence for delivery into the injured intestinal epithelial cell

BACKGROUND: Severe injury results in intestinal barrier dysfunction that may be responsible for significant morbidity and mortality. We postulated that mining a peptide library that was displayed on phage would identify peptide sequences that bind and internalize into the gut epithelium following in...

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Vydáno v:Surgery
Hlavní autoři: Costantini, Todd W., Putnam, James G., Sawada, Ritsuko, Baird, Andrew, Loomis, William H., Eliceiri, Brian P., Bansal, Vishal, Coimbra, Raul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251594/
https://ncbi.nlm.nih.gov/pubmed/19628075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.05.007
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