Tetherin/BST-2 is essential for the formation of the intracellular virus-containing compartment in HIV-infected macrophages

HIV-1 assembly and release occurs at the plasma membrane in T lymphocytes, while intracellular sites of virus assembly or accumulation are apparent in macrophages. The host protein tetherin (BST-2) inhibits HIV release from the plasma membrane by retaining viral particles at the cell surface, but th...

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Détails bibliographiques
Auteurs principaux: Chu, Hin, Wang, Jaang-Jiun, Qi, Mingli, Yoon, Jeong-Joong, Chen, Xuemin, Wen, Xiaoyun, Hammonds, Jason, Ding, Lingmei, Spearman, Paul
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444820/
https://ncbi.nlm.nih.gov/pubmed/22980332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.07.011
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