Transglutaminase Inhibition Protects against Oxidative Stress-Induced Neuronal Death Downstream of Pathological ERK Activation

Molecular deletion of transglutaminase 2 (TG2) has been shown to improve function and survival in a host of neurological conditions including stroke, Huntington's disease, and Parkinson's disease. However, unifying schemes by which these cross-linking or polyaminating enzymes participate b...

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Hlavní autoři: Basso, Manuela, Berlin, Jill, Xia, Li, Sleiman, Sama F., Ko, Brendan, Haskew-Layton, Renee, Kim, Eunhee, Antonyak, Marc A., Cerione, Richard A., Iismaa, Siiri E., Willis, Dianna, Cho, Sunghee, Ratan, Rajiv R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444816/
https://ncbi.nlm.nih.gov/pubmed/22573678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3353-11.2012
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