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Hydroxynitrile Lyases with α/β-Hydrolase Fold: Two Enzymes with Almost Identical 3D Structures but Opposite Enantioselectivities and Different Reaction Mechanisms

Hydroxynitrile lyases (HNLs) catalyze the cleavage of cyanohydrins to yield hydrocyanic acid (HCN) and the respective carbonyl compound and are key enzymes in the process of cyanogenesis in plants. In organic syntheses, HNLs are used as biocatalysts for the formation of enantiopure cyanohydrins. We...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Andexer, Jennifer N, Staunig, Nicole, Eggert, Thorsten, Kratky, Christoph, Pohl, Martina, Gruber, Karl
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: WILEY-VCH Verlag 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444685/
https://ncbi.nlm.nih.gov/pubmed/22851196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200239
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