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Na(+) and K(+) ion imbalances in Alzheimer’s disease

Alzheimer’s disease (AD) is associated with impaired glutamate clearance and depressed Na(+)/K(+) ATPase levels in AD brain that might lead to a cellular ion imbalance. To test this hypothesis, [Na(+)] and [K(+)] were analyzed in postmortem brain samples of 12 normal and 16 AD individuals, and in ce...

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Autors principals: Vitvitsky, Victor M., Garg, Sanjay K., Keep, Richard F., Albin, Roger L., Banerjee, Ruma
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444663/
https://ncbi.nlm.nih.gov/pubmed/22820549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.07.004
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