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Differential Dependence on Cysteine from Transsulfuration versus Transport During T Cell Activation
The synthesis of glutathione, a major cellular antioxidant with a critical role in T cell proliferation, is limited by cysteine. In this study, we evaluated the contributions of the x(C)(-) cystine transporter and the transsulfuration pathway to cysteine provision for glutathione synthesis and antio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110100/ https://ncbi.nlm.nih.gov/pubmed/20673163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3496 |
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