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Differential Dependence on Cysteine from Transsulfuration versus Transport During T Cell Activation

The synthesis of glutathione, a major cellular antioxidant with a critical role in T cell proliferation, is limited by cysteine. In this study, we evaluated the contributions of the x(C)(-) cystine transporter and the transsulfuration pathway to cysteine provision for glutathione synthesis and antio...

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Detaylı Bibliyografya
Asıl Yazarlar: Garg, Sanjay K., Yan, Zhonghua, Vitvitsky, Victor, Banerjee, Ruma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110100/
https://ncbi.nlm.nih.gov/pubmed/20673163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3496
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