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Differential Effects of Lovastatin on Cisplatin Responses in Normal Human Mesothelial Cells versus Cancer Cells: Implication for Therapy

The cancer killing efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is limited by their side effects to normal tissues. Therefore, research efforts optimizing the safety and efficacy of those agents are clinically relevant. We did screen for agents that specifically protect norm...

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Autors principals: Shi, Yandong, Felley-Bosco, Emanuela, Marti, Thomas M., Stahel, Rolf A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444484/
https://ncbi.nlm.nih.gov/pubmed/23028957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045354
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