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Detrimental Effects of RNAi: A Cautionary Note on Its Use in Drosophila Ageing Studies

RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because it does not appear to have any non-specific effects on ageing-related traits in that model organism. We show here that ubiquitous, adult-onse...

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Détails bibliographiques
Auteurs principaux: Alic, Nazif, Hoddinott, Matthew P., Foley, Andrea, Slack, Cathy, Piper, Matthew D. W., Partridge, Linda
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444450/
https://ncbi.nlm.nih.gov/pubmed/23028964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045367
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