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Blood flow and oxygen delivery to human brain during functional activity: Theoretical modeling and experimental data

Coupling of cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO(2)) in physiologically activated brain states remains the subject of debates. Recently it was suggested that CBF is tightly coupled to oxidative metabolism in a nonlinear fashion. As part of this hypothesis, mathemati...

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Detalhes bibliográficos
Main Authors: Mintun, Mark A., Lundstrom, Brian N., Snyder, Abraham Z., Vlassenko, Andrei G., Shulman, Gordon L., Raichle, Marcus E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34443/
https://ncbi.nlm.nih.gov/pubmed/11381119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111164398
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