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Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain

The factors regulating cerebral blood flow (CBF) changes in physiological activation remain the subject of great interest and debate. Recent experimental studies suggest that an increase in cytosolic NADH mediates increased blood flow in the working brain. Lactate injection should elevate NADH level...

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Detalhes bibliográficos
Main Authors: Mintun, Mark A., Vlassenko, Andrei G., Rundle, Melissa M., Raichle, Marcus E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC327204/
https://ncbi.nlm.nih.gov/pubmed/14704276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307457100
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