Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes Prevention Program

AIMS/HYPOTHESIS: Individuals with impaired glucose tolerance have increased proinsulin levels, despite normal glucose or C-peptide levels. In the Diabetes Prevention Program (DPP), increased proinsulin levels predicted type 2 diabetes and proinsulin levels were significantly reduced following treatm...

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Main Authors: Majithia, A. R., Jablonski, K. A., McAteer, J. B., Mather, K. J., Goldberg, R. B., Kahn, S. E., Florez, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444290/
https://ncbi.nlm.nih.gov/pubmed/21779873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2234-1
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