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The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis

Copper plays a fundamental role in the biochemistry of all aerobic organisms. The delivery of this metal to specific intracellular targets is mediated by metallochaperones. To elucidate the role of the metallochaperone Atox1, we analyzed mice with a disruption of the Atox1 locus. Atox1(−/−) mice fai...

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Détails bibliographiques
Auteurs principaux: Hamza, Iqbal, Faisst, Anja, Prohaska, Joseph, Chen, Joseph, Gruss, Peter, Gitlin, Jonathan D.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC34441/
https://ncbi.nlm.nih.gov/pubmed/11391006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111058498
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