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Evolution of a Pathway to Novel Long-Chain Carotenoids
Using methods of laboratory evolution to force the C(30) carotenoid synthase CrtM to function as a C(40) synthase, followed by further mutagenesis at functionally important amino acid residues, we have discovered that synthase specificity is controlled at the second (rearrangement) step of the two-s...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344396/ https://ncbi.nlm.nih.gov/pubmed/14973014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.5.1531-1536.2004 |
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