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Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy

‘Tomacula’ and myelin outfoldings are striking neuropathological features of a diverse group of inherited demyelinating neuropathies. Whereas the underlying genetic defects are well known, the molecular mechanisms of tomacula formation have remained obscure. We hypothesized that they are caused by u...

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Main Authors: Goebbels, Sandra, Oltrogge, Jan H, Wolfer, Susanne, Wieser, Georg L, Nientiedt, Tobias, Pieper, Alexander, Ruhwedel, Torben, Groszer, Matthias, Sereda, Michael W, Nave, Klaus-Armin
Formáid: Artigo
Teanga:Inglês
Foilsithe: WILEY-VCH Verlag 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443946/
https://ncbi.nlm.nih.gov/pubmed/22488882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200227
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