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Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy

‘Tomacula’ and myelin outfoldings are striking neuropathological features of a diverse group of inherited demyelinating neuropathies. Whereas the underlying genetic defects are well known, the molecular mechanisms of tomacula formation have remained obscure. We hypothesized that they are caused by u...

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Bibliografiset tiedot
Päätekijät: Goebbels, Sandra, Oltrogge, Jan H, Wolfer, Susanne, Wieser, Georg L, Nientiedt, Tobias, Pieper, Alexander, Ruhwedel, Torben, Groszer, Matthias, Sereda, Michael W, Nave, Klaus-Armin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: WILEY-VCH Verlag 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443946/
https://ncbi.nlm.nih.gov/pubmed/22488882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200227
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