Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy

‘Tomacula’ and myelin outfoldings are striking neuropathological features of a diverse group of inherited demyelinating neuropathies. Whereas the underlying genetic defects are well known, the molecular mechanisms of tomacula formation have remained obscure. We hypothesized that they are caused by u...

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Autores principales: Goebbels, Sandra, Oltrogge, Jan H, Wolfer, Susanne, Wieser, Georg L, Nientiedt, Tobias, Pieper, Alexander, Ruhwedel, Torben, Groszer, Matthias, Sereda, Michael W, Nave, Klaus-Armin
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2012
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443946/
https://ncbi.nlm.nih.gov/pubmed/22488882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200227
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