Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53

Poly-ADP ribose polymerase (PARP) inhibitors have shown promise in the treatment of human malignancies characterized by deficiencies in the DNA damage repair proteins BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectiveness of PARP inhibitors in targeting ataxia-telangie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Williamson, Chris T, Kubota, Eiji, Hamill, Jeffrey D, Klimowicz, Alexander, Ye, Ruiqiong, Muzik, Huong, Dean, Michelle, Tu, LiRen, Gilley, David, Magliocco, Anthony M, McKay, Bruce C, Bebb, D Gwyn, Lees-Miller, Susan P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: WILEY-VCH Verlag 2012
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443945/
https://ncbi.nlm.nih.gov/pubmed/22416035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200229
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