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Thyroid hormone receptors are tumor suppressors in a mouse model of metastatic follicular thyroid carcinoma
Aberrant expression and mutations of thyroid hormone receptor genes (TRs) are closely associated with several types of human cancers. To test the hypothesis that TRs could function as tumor suppressors, we took advantage of mice with deletion of all functional TRs (TRα1(−/− )TRβ(−/−)mice). As these...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443884/ https://ncbi.nlm.nih.gov/pubmed/20062085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.476 |
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