Kinetics and thermodynamics of T cell receptor– autoantigen interactions in murine experimental autoimmune encephalomyelitis

In the current study, cellular and molecular approaches have been used to analyze the biophysical nature of T cell receptor (TCR)–peptide MHC (pMHC) interactions for two autoreactive TCRs. These two TCRs recognize the N-terminal epitope of myelin basic protein (MBP1–11) bound to the MHC class II pro...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Garcia, K. Christopher, Radu, Caius G., Ho, Joseph, Ober, Raimund J., Ward, E. Sally
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2001
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11391002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111161198
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