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Kinetics and thermodynamics of T cell receptor– autoantigen interactions in murine experimental autoimmune encephalomyelitis

In the current study, cellular and molecular approaches have been used to analyze the biophysical nature of T cell receptor (TCR)–peptide MHC (pMHC) interactions for two autoreactive TCRs. These two TCRs recognize the N-terminal epitope of myelin basic protein (MBP1–11) bound to the MHC class II pro...

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Detalhes bibliográficos
Main Authors: Garcia, K. Christopher, Radu, Caius G., Ho, Joseph, Ober, Raimund J., Ward, E. Sally
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34436/
https://ncbi.nlm.nih.gov/pubmed/11391002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111161198
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