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A Retro-inhibition Approach Reveals a Tumor Cell-Autonomous Response to Rapamycin in Head and Neck Squamous Carcinoma
Emerging evidence supporting the activation of the Akt-mTOR signaling network in head and neck squamous cell carcinoma (HNSCC) progression has provided the rationale for exploring the therapeutic potential of inhibiting this pathway for HNSCC treatment. Indeed, rapamycin, a clinically relevant mTOR...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443567/ https://ncbi.nlm.nih.gov/pubmed/18281490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-1756 |
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