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Combining Asymmetric Catalysis with Natural Product Functionalization through Enantioselective α-Fluorination

[Image: see text] An examination into the derivatization of various natural products using newly developed α-fluorination methodology is disclosed. An activated ketene enolate, generated from an acid chloride, is allowed to react with an electrophilic fluorine source (NFSi). Quenching the reaction w...

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Hlavní autoři: Erb, Jeremy, Alden-Danforth, Ethan, Kopf, Nathan, Scerba, Michael T., Lectka, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443555/
https://ncbi.nlm.nih.gov/pubmed/20039641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9024072
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