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Catalytic, Asymmetric α-Fluorination of Acid Chlorides: Dual Metal-Ketene Enolate Activation
[Image: see text] In this Communication, we disclose a catalytic, highly enantioselective (up to >99% ee) α-fluorination of acid chlorides to produce a variety of optically active carboxylic acid derivatives from readily accessible and commercially available starting materials. The reaction depen...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651145/ https://ncbi.nlm.nih.gov/pubmed/19049284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807792c |
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