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Salivary Gland Hypofunction Induced by Activation of Innate Immunity is Dependent on Type I Interferon Signaling

BACKGROUND: Activation of innate immunity through polyinosinic:polycytidylic acid (poly(I:C)) causes acute salivary gland hypofunction. Since a major consequence of poly(I:C) treatment is type I interferon (IFN) production, this study was undertaken to investigate their role in salivary gland dysfun...

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Detalhes bibliográficos
Main Authors: Nandula, Seshagiri-Rao, Dey, Paromita, Corbin, Kathryn L., Nunemaker, Craig, Bagavant, Harini, Deshmukh, Umesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443546/
https://ncbi.nlm.nih.gov/pubmed/22672212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0714.2012.01181.x
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