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Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus

We inoculated BALB/c mice deficient in STAT6 (STAT6(−/−)) and their wild-type (wt) littermates (STAT6(+/+)) with the natural mouse pathogen, ectromelia virus (EV). STAT6(−/−) mice exhibited increased resistance to generalized infection with EV when compared with STAT6(+/+) mice. In the spleens and l...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mahalingam, Surendran, Karupiah, Gunasegaran, Takeda, Kiyoshi, Akira, Shizuo, Matthaei, Klaus I., Foster, Paul S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111151098
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