Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus

We inoculated BALB/c mice deficient in STAT6 (STAT6(−/−)) and their wild-type (wt) littermates (STAT6(+/+)) with the natural mouse pathogen, ectromelia virus (EV). STAT6(−/−) mice exhibited increased resistance to generalized infection with EV when compared with STAT6(+/+) mice. In the spleens and l...

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Bibliographische Detailangaben
Hauptverfasser: Mahalingam, Surendran, Karupiah, Gunasegaran, Takeda, Kiyoshi, Akira, Shizuo, Matthaei, Klaus I., Foster, Paul S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC34435/
https://ncbi.nlm.nih.gov/pubmed/11371617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111151098
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