Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex

The alloreactive human T cell clone MBM15 was found to exhibit dual specificity recognizing both an antigen in the context of the HLA class I A2 molecule and an antigen in the context of the HLA class II DR1. We demonstrated that the dual reactivity that was mediated via a single clonal T cell popul...

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Autors principals: Heemskerk, Mirjam H. M., de Paus, Roelof A., Lurvink, Ellie G. A., Koning, Frits, Mulder, Arend, Willemze, Roel, van Rood, Jon J., Falkenburg, J. H. Frederik
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC34434/
https://ncbi.nlm.nih.gov/pubmed/11381117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111162298
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