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Oxidative Stress as a Therapeutic Target in Globoid Cell Leukodystrophy
Globoid Cell Leukodystrohpy (GLD, Krabbe Disease) is a lysosomal storage disease, resulting from the genetic deficiency of Galactosylceramidase (GALC). This disease is marked by accumulation of the cytotoxic lipid psychosine (Psy). Psychosine is known to induce oxidative stress in cultured cells, an...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443330/ https://ncbi.nlm.nih.gov/pubmed/22849820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.07.013 |
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