Allospecific CD4(+) Effector Memory T Cells Do Not Induce Graft-versus-Host Disease in Mice

We studied whether allospecific CD4(+) effector memory T cells (T(EM)) could induce graft-versus-host disease (GVHD) using a novel GVHD model solely induced by CD4(+) T cell receptor transgenic TEa cells. Allospecific T(EM) generated in a lymphopenic host bore a typical memory phenotype. Moreover, t...

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Bibliographic Details
Main Authors: Zhang, Ping, Wu, Jieying, Deoliveira, Divino, Chao, Nelson J., Chen, Benny J.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443280/
https://ncbi.nlm.nih.gov/pubmed/22809867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.07.009
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