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Drosophila TRPML is Required For TORC1 Activation
Loss-of-function mutations in TRPML1 (Transient Receptor Potential Mucolipin 1) cause a lysosomal storage disorder called mucolipidosis type IV (MLIV). Previously, we established a Drosophila model for MLIV by knocking out the single TRPML1 homolog expressed in flies [1]. The mutant animals displaye...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443270/ https://ncbi.nlm.nih.gov/pubmed/22863314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.06.055 |
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