Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

Mutations in the critical chromatin modifier ATRX and mutations in CIC and FUBP1, which are potent regulators of cell growth, have been discovered in specific subtypes of gliomas, the most common type of primary malignant brain tumors. However, the frequency of these mutations in many subtypes of gl...

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Main Authors: Jiao, Yuchen, Killela, Patrick J., Reitman, Zachary J., Rasheed, B. Ahmed, Heaphy, Christopher M., de Wilde, Roeland F., Rodriguez, Fausto J., Rosemberg, Sergio, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi, Bettegowda, Chetan, Agrawal, Nishant, Lipp, Eric, Pirozzi, Christopher J., Lopez, Giselle Y., He, Yiping, Friedman, Henry S., Friedman, Allan H., Riggins, Gregory J., Holdhoff, Matthias, Burger, Peter, McLendon, Roger E., Bigner, Darell D., Vogelstein, Bert, Meeker, Alan K., Kinzler, Kenneth W., Papadopoulos, Nickolas, Diaz, Luis A., Yan, Hai
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443254/
https://ncbi.nlm.nih.gov/pubmed/22869205
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