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CD80 and CD86 Differentially Regulate Mechanical Interactions of T-Cells with Antigen-Presenting Dendritic Cells and B-Cells

Functional T-cell responses are initiated by physical interactions between T-cells and antigen-presenting cells (APCs), including dendritic cells (DCs) and B-cells. T-cells are activated more effectively by DCs than by B-cells, but little is known about the key molecular mechanisms that underpin the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Tong Seng, Goh, James Kang Hao, Mortellaro, Alessandra, Lim, Chwee Teck, Hämmerling, Günter J., Ricciardi-Castagnoli, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443229/
https://ncbi.nlm.nih.gov/pubmed/23024807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045185
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