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Protein Trans-Splicing of an Atypical Split Intein Showing Structural Flexibility and Cross-Reactivity
Inteins catalyze a protein splicing reaction to excise the intein from a precursor protein and join the flanking sequences (exteins) with a peptide bond. In a split intein, the intein fragments (I(N) and I(C)) can reassemble non-covalently to catalyze a trans-splicing reaction that joins the exteins...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443213/ https://ncbi.nlm.nih.gov/pubmed/23024818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045355 |
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