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Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice

Recent findings suggest that neurons can efficiently repair oxidatively damaged DNA, and that both DNA damage and repair are enhanced by activation of excitatory glutamate receptors. However, in pathological conditions such as ischemic stroke, excessive DNA damage can trigger the death of neurons. O...

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Main Authors: Canugovi, Chandrika, Yoon, Jeong Seon, Feldman, Neil H., Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443144/
https://ncbi.nlm.nih.gov/pubmed/22927410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204156109
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