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Pyranopterin conformation defines the function of molybdenum and tungsten enzymes

We have analyzed the conformations of 319 pyranopterins in 102 protein structures of mononuclear molybdenum and tungsten enzymes. These span a continuum between geometries anticipated for quinonoid dihydro, tetrahydro, and dihydro oxidation states. We demonstrate that pyranopterin conformation is co...

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Bibliografiska uppgifter
Huvudupphovsmän: Rothery, Richard A., Stein, Benjamin, Solomonson, Matthew, Kirk, Martin L., Weiner, Joel H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443133/
https://ncbi.nlm.nih.gov/pubmed/22927383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200671109
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