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Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

BACKGROUND: Growth hormone (GH) stimulates whole-body lipid oxidation, but its regulation of muscle lipid oxidation is not clearly defined. Mice with a skeletal muscle-specific knockout of the GH receptor (mGHRKO model) are protected from high fat diet (HFD)–induced insulin resistance and display in...

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Autors principals: Vijayakumar, Archana, Wu, YingJie, Buffin, Nicholas J., Li, Xiaosong, Sun, Hui, Gordon, Ronald E., Yakar, Shoshana, LeRoith, Derek
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443095/
https://ncbi.nlm.nih.gov/pubmed/23024761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044777
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