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A bone marrow toxicity model for (223)Ra alpha-emitter radiopharmaceutical therapy

PURPOSE: Ra-223, an α-particle emitting bone-seeking radionuclide, has recently been used in clinical trials for osseous metasteses of prostate cancer. We investigated the relationship between absorbed fraction-based red marrow dosimetry and cell level-dosimetry using a model that accounts for the e...

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Huvudupphovsmän: Hobbs, Robert F, Song, Hong, Watchman, Christopher J, Bolch, Wesley E, Aksnes, Anne-Kirsti, Ramdahl, Thomas, Flux, Glenn D, Sgouros, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442928/
https://ncbi.nlm.nih.gov/pubmed/22546715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/57/10/3207
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