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DNA excision repair: Where do all the dimers go?

Exposure of cells to UV light from the sun causes the formation of pyrimidine dimers in DNA that have the potential to lead to mutation and cancer. In humans, pyrimidine dimers are removed from the genome in the form of ~30 nt-long oligomers by concerted dual incisions. Though nearly 50 y of excisio...

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Détails bibliographiques
Auteurs principaux: Kemp, Michael G., Sancar, Aziz
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442910/
https://ncbi.nlm.nih.gov/pubmed/22825251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21126
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