Carregant...

Ligand-mimicking Receptor Variant Discloses Binding and Activation Mode of Prolactin-releasing Peptide

The prolactin-releasing peptide receptor and its bioactive RF-amide peptide (PrRP20) have been investigated to explore the ligand binding mode of peptide G-protein-coupled receptors (GPCRs). By receptor mutagenesis, we identified the conserved aspartate in the upper transmembrane helix 6 (Asp(6.59))...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Rathmann, Daniel, Lindner, Diana, DeLuca, Stephanie H., Kaufmann, Kristian W., Meiler, Jens, Beck-Sickinger, Annette G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442549/
https://ncbi.nlm.nih.gov/pubmed/22778259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349852
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!