Phosphatase of Regenerating Liver 2 (PRL2) Is Essential for Placental Development by Down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and Activating Akt Protein

The PRL (phosphatase of regenerating liver) phosphatases are implicated in the control of cell proliferation and invasion. Aberrant PRL expression is associated with progression and metastasis of multiple cancers. However, the specific in vivo function of the PRLs remains elusive. Here we show that...

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Detalhes bibliográficos
Main Authors: Dong, Yuanshu, Zhang, Lujuan, Zhang, Sheng, Bai, Yunpeng, Chen, Hanying, Sun, Xiaoxin, Yong, Weidong, Li, Wei, Colvin, Stephanie C., Rhodes, Simon J., Shou, Weinian, Zhang, Zhong-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442547/
https://ncbi.nlm.nih.gov/pubmed/22791713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393462
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