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ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemical cues to guide cellular decision making are not well defined. Here we investigate mechanisms by whi...

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Bibliografiska uppgifter
Huvudupphovsmän: Allen, Jessica L., Cooke, Margaret E., Alliston, Tamara
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442419/
https://ncbi.nlm.nih.gov/pubmed/22833566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0172
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