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ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemical cues to guide cellular decision making are not well defined. Here we investigate mechanisms by whi...

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Detalhes bibliográficos
Main Authors: Allen, Jessica L., Cooke, Margaret E., Alliston, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442419/
https://ncbi.nlm.nih.gov/pubmed/22833566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0172
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