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ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemical cues to guide cellular decision making are not well defined. Here we investigate mechanisms by whi...

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書誌詳細
主要な著者: Allen, Jessica L., Cooke, Margaret E., Alliston, Tamara
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442419/
https://ncbi.nlm.nih.gov/pubmed/22833566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0172
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