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ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation

Cells encounter physical cues such as extracellular matrix (ECM) stiffness in a microenvironment replete with biochemical cues. However, the mechanisms by which cells integrate physical and biochemical cues to guide cellular decision making are not well defined. Here we investigate mechanisms by whi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Allen, Jessica L., Cooke, Margaret E., Alliston, Tamara
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442419/
https://ncbi.nlm.nih.gov/pubmed/22833566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-03-0172
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