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CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies
Ubiquitination of the epidermal growth factor receptor (EGFR) by cbl and its cognate adaptor cbl-interacting protein of 85 kDa (CIN85) is known to play an essential role in directing this receptor to the lysosome for degradation. The mechanisms by which this ubiquitin modification is regulated are n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442408/ https://ncbi.nlm.nih.gov/pubmed/22833562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0666 |
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