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Elevated VEGF Receptor-2 Abundance Contributes to Increased Angiogenesis in VEGF Receptor-1 Deficient Mice
BACKGROUND: Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1) is a potential therapeutic target for cardiovascular diseases, but its role in angiogenesis remains controversial. While germline Vegfr-1(−/−) embryos die of abnormal vascular development in association with excessive endothel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442373/ https://ncbi.nlm.nih.gov/pubmed/22753193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.091603 |
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