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Elevated VEGF Receptor-2 Abundance Contributes to Increased Angiogenesis in VEGF Receptor-1 Deficient Mice

BACKGROUND: Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1) is a potential therapeutic target for cardiovascular diseases, but its role in angiogenesis remains controversial. While germline Vegfr-1(−/−) embryos die of abnormal vascular development in association with excessive endothel...

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Hlavní autoři: Ho, Vivienne C., Duan, Li-Juan, Cronin, Chunxia, Liang, Bruce T., Fong, Guo-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442373/
https://ncbi.nlm.nih.gov/pubmed/22753193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.091603
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