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Several Days of CPEB-Dependent Local Protein Synthesis Are Required to Stabilize Synaptic Growth for Persistence of Long-Term Facilitation in Aplysia

The time course of the requirement for local protein synthesis in the stabilization of learning-related synaptic growth and the persistence of long-term memory was examined using Aplysia bifurcated sensory neuron-motor neuron cultures. We find that following repeated pulses of serotonin (5-HT) the l...

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Detalhes bibliográficos
Main Authors: Miniaci, Maria Concetta, Kim, Joung-Hun, Puthenveettil, Sathyanarayanan, Si, Kausik, Zhu, Huixiang, Kandel, Eric R., Bailey, Craig H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442368/
https://ncbi.nlm.nih.gov/pubmed/18817739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.07.036
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