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A Single Aplysia Neurotrophin Mediates Synaptic Facilitation via Differentially Processed Isoforms Secreted as Mature or Precursor Forms

Neurotrophins control the development and adult plasticity of the vertebrate nervous system. Failure to identify invertebrate neurotrophin orthologs, however, has precluded studies in invertebrate models, limiting understanding of fundamental aspects of neurotrophin biology and function. We identifi...

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Detalhes bibliográficos
Main Authors: Kassabov, Stefan R., Choi, Yun-Beom, Karl, Kevin A., Vishwasrao, Harshad D., Bailey, Craig H., Kandel, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045214/
https://ncbi.nlm.nih.gov/pubmed/23562154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.03.008
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